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1.
Curr Oncol Rep ; 24(7): 835-842, 2022 07.
Article in English | MEDLINE | ID: covidwho-1750839

ABSTRACT

PURPOSE OF REVIEW: Patients with hematological malignancies are recognized for their high susceptibility and increased risk of developing infections associated with immunosuppression that can be caused by the infection itself or by the treatments that condition a decrease in the humoral and T lymphocyte response, so this review attempts to gather the main bacterial, viral, parasitic, and fungal agents that affect them and give recommendations for their approach and diagnosis. RECENT FINDINGS: In recent years, with the discovery and use of new therapies including immunological and targeted treatments, it has been possible to improve the survival and response of patients with hematological malignancies; however, antimicrobial resistance has also increased; we have faced new and unknown microorganisms, such as the SARS-CoV-2 that caused the COVID-19 pandemic in the past year, and therefore, new risks and more severe infections are presented. We present a review of the different circumstances where hematological malignancies increased the risk of infections and which microorganisms affect these patients, their characteristics, and the suggested prophylaxis.


Subject(s)
COVID-19 , Hematologic Neoplasms , Anti-Bacterial Agents/therapeutic use , Antibiotic Prophylaxis , Hematologic Neoplasms/complications , Hematologic Neoplasms/drug therapy , Humans , Pandemics , SARS-CoV-2
3.
BMJ Case Rep ; 13(6)2020 Jun 24.
Article in English | MEDLINE | ID: covidwho-614885

ABSTRACT

The presence of rhabdomyolysis secondary to multiple infections has been reported, predominantly viral, but also bacterial and fungal. It is well known that COVID-19 can present a wide variety of complications during the course of infection; however, the presence of rhabdomyolysis as an initial condition has not been reported so far. We report a case of rhabdomyolysis as an initial presentation in a patient diagnosed with SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection.


Subject(s)
Betacoronavirus , Coronavirus Infections/complications , Coronavirus Infections/diagnostic imaging , Lung/diagnostic imaging , Pneumonia, Viral/complications , Pneumonia, Viral/diagnostic imaging , Rhabdomyolysis/etiology , Aged , Anti-Bacterial Agents/therapeutic use , Antibodies, Monoclonal, Humanized/therapeutic use , Anticoagulants/therapeutic use , Azithromycin/therapeutic use , Bicarbonates/therapeutic use , COVID-19 , Ceftriaxone/therapeutic use , Coronavirus Infections/therapy , Cytochrome P-450 CYP3A Inhibitors/therapeutic use , Enoxaparin/therapeutic use , Enzyme Inhibitors/therapeutic use , Fluid Therapy , Humans , Hydroxychloroquine/therapeutic use , Lopinavir/therapeutic use , Male , Pandemics , Pneumonia, Viral/therapy , Respiration, Artificial , Rhabdomyolysis/diagnosis , Rhabdomyolysis/therapy , Ritonavir/therapeutic use , SARS-CoV-2 , Tomography, X-Ray Computed/methods , Treatment Outcome
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